Human phosphorylated Tau217 Protein
Catalog# HA211033
Human phosphorylated Tau217 Protein
Product Information
Product name
Human phosphorylated Tau217 Protein
Catalog No.
HA211033
Accession
P10636-8
Protein construction
Source
HEK293
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
Tau, also known as MAPT (microtubule-associated protein tau), MAPTL, MTBT1 or TAU, is a 758 amino acid protein that localizes to the cytoplasm, as well as to the cytoskeleton and the cell membrane, and contains four Tau/MAP repeats. Expressed in neuronal tissue and existing as multiple alternatively spliced isoforms, Tau functions to promote microtubule assembly and stability and is thought to be involved in the maintenance of neuronal polarity. Tau may also link microtubules with neural plasma membrane components and, addition to its role in microtubule stability, is also necessary for cytoskeletal plasticity. Tau is highly subject to a variety of post-translational modifications, including phosphorylation on serine and threonine residues, polyubiquitination (and subsequent proteasomal degradation) and glycation of specific Tau isoforms. Defects in the gene encoding Tau are associated with Alzheimers disease, pallido-ponto-nigral degeneration (PPND), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP).
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
Products with the same target and pathway
Human GTPase HRAS, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human BACE1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human ATF6, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human NFL, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human S100A12,Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human SIRPA, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human GDNF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IKK gamma/NEMO, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Insulin, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human TNF RI/TNFRSF1A, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human HSPA1A, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human GADD45B, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human PMCA1/ATP2B1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Caspase-9/CASP9, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Apolipoprotein E, Tag Free
Application:
Reactivity: Human
Conjugate:
Human SNAP25, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human APP, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CNTF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Beta-synuclein/SNCB, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human RAGE, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human ICAM-3/CD50, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human DVL2, C Twin Strep, Flag Protein
Application:
Reactivity: Human
Conjugate:
Human SPR, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Sorcin/SRI, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human EIF2AK3/PERK, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human M-CSF/CSF1 (33-255), C His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human AGRP, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL1R1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human PARK7/DJ-1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human NPTX2, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human TNF-alpha, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Agrin, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Syndecan-1/CD138, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Fas/TNFRSF6/CD95, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human UCH-L1/PGP9.5, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human alpha-Synuclein, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Neurogranin, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human KIF5B, N-Twin Strep, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Thioredoxin/TXN, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Enolase 2/ENO2, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CNTF, N-His Tag, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human M-CSF/CSF1 (33-190), Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human C-Reactive Protein/CRP, C-His, Flag Tag
Application:
Reactivity: Human
Conjugate:
Human Apolipoprotein E/APOE4 (C130R), Tag Free
Application:
Reactivity: Human
Conjugate:
Human Cystatin C, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human 14-3-3 zeta, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human SP-D/SFTPD, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human TNF-alpha, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human DKK1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human NG2/MCSP/CSPG4, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CDC42, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human NRG1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human EPHA2, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Transthyretin/TTR, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human TGF-beta RII, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human MAPK12, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human DLK1, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human RAC1, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Tau/Tau758, C-His (isoform PNS-tau) Protein
Application:
Reactivity: Human
Conjugate:
Human Ferritin heavy chain 1/FTH1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CASQ1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human ANXA6, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Siglec-7/CD328, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CRKL, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CASQ2, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human VSNL1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-1 beta/IL1B, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human NR4A2/NURR1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human ICAM-1/CD54, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human GFAP, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Annexin A6/ANXA6, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human MAP4K1/HPK1, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human PPID, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-1 alpha/IL1A, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human NRG1, C-Flag (176-246) Protein
Application:
Reactivity: Human
Conjugate:
Human Tau/Tau441, C-His (isoform 2N4R) Protein
Application:
Reactivity: Human
Conjugate:
Human COX5A, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human GADD45A, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human NCAM1/CD56, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD14, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
