Human PMCA1/ATP2B1, C-His Tag Protein
Catalog# HA210711
Human PMCA1/ATP2B1, C-His Tag Protein
Product Information
Product name
Human PMCA1/ATP2B1, C-His Tag Protein
Catalog No.
HA210711
Predicted molecular mass
24.5 kD
Protein construction description
A DNA sequence encoding the human PMCA1/ATP2B1 protein (P20020) (Thr 481-Asp 684) was expressed with a His tag at the C-terminus.
Accession
P20020
Protein construction
Source
E.coli
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis. Plays a role in blood pressure regulation through regulation of intracellular calcium concentration and nitric oxide production leading to regulation of vascular smooth muscle cells vasoconstriction. Positively regulates bone mineralization through absorption of calcium from the intestine. Plays dual roles in osteoclast differentiation and survival by regulating RANKL-induced calcium oscillations in preosteoclasts and mediating calcium extrusion in mature osteoclasts. Regulates insulin sensitivity through calcium/calmodulin signaling pathway by regulating AKT1 activation and NOS3 activation in endothelial cells.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
Products with the same target and pathway
Human FSH Beta, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Caspase-9/CASP9, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CNTF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human PDE1B, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human SPR, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Sorcin/SRI, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human GHRL, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Syndecan-1/CD138, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Enolase 2/ENO2, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CNTF, N-His Tag, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human C-Reactive Protein/CRP, C-His, Flag Tag
Application:
Reactivity: Human
Conjugate:
Human Apolipoprotein E/APOE4 (C130R), Tag Free
Application:
Reactivity: Human
Conjugate:
Human Cystatin C, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human NRG1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human DLK1, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human RAC1, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CASQ1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human ANXA6, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Siglec-7/CD328, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CASQ2, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human VSNL1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human NR4A2/NURR1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human EGF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human ICAM-1/CD54, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human PDGF-B, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human GFAP, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Annexin A6/ANXA6, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human NRG1, C-Flag (176-246) Protein
Application:
Reactivity: Human
Conjugate:
Human Tau/Tau441, C-His (isoform 2N4R) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human NCAM1/CD56, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human PDGF-AA, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
