Human Thrombomodulin, C-His Tag Protein
Catalog# HA211324
Human Thrombomodulin, C-His Tag Protein
Product Information
Product name
Human Thrombomodulin, C-His Tag Protein
Catalog No.
HA211324
Predicted molecular mass
31 kD
Protein construction description
A DNA sequence encoding the human Thrombomodulin protein (P07204) (Ala 239-Ser 515) was expressed with a His tag at the C-terminus.
Accession
P07204
Protein construction
Thrombomodulin (239-515)
His
Source
HEK293
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
Thrombomodulin functions as a cofactor in the thrombin-induced activation of protein C in the anticoagulant pathway by forming a 1:1 stoichiometric complex with thrombin. This raises the speed of protein C activation thousandfold. Thrombomodulin-bound thrombin has procoagulant effect at the same time by inhibiting fibrinolysis by cleaving thrombin-activatable fibrinolysis inhibitor (TAFI, aka carboxypeptidase B2) into its active form. Thrombomodulin is a glycoprotein on the surface of endothelial cells that, in addition to binding thrombin, regulates C3b inactivation by factor I. Mutations in the thrombomodulin gene (THBD) have also been reported to be associated with atypical hemolytic-uremic syndrome (aHUS).
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
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Human FABP3 / H-FABP, Tag Free Protein
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Human GATA4, Tag Free Protein
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Human CCL19 / MIP-3 beta, Tag Free Protein
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Human SIRPA, Tag Free Protein
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Human Alpha-fetoprotein, C-His Tag
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Human CCL17/TARC, Tag Free Protein
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Human TRAIL/TNFSF10, C-His Tag Protein
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Human CD48, C-His Tag Protein
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Human CD30 Ligand / TNFSF8, Tag Free Protein
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Reactivity: Human
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Human IKK gamma/NEMO, Tag Free Protein
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Reactivity: Human
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Human MRC1/CD206, C-His Tag Protein
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Reactivity: Human
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Human IL-22, C-His, Flag Tag Protein
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Human Antithrombin III, C-His Tag Protein
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Human TNF RI/TNFRSF1A, Tag Free (ECD) Protein
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Human CXCL10, C-Flag Tag Protein
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Human Leptin Receptor, C-His Tag (ECD) Protein
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Human IL-7, C-His, Flag Tag Protein
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Human IL-11, Tag Free Protein
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Reactivity: Human
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Human TLR3, C-His Tag Protein
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Reactivity: Human
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Human IL-7 R alpha / CD127, Tag Free Protein
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Reactivity: Human
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Human BAFF/TNFSF13B/CD257 Trimer design, N-hFc Tag Protein
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Human DR3/TNFRSF25, Tag Free Protein
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Reactivity: Human
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Human Myoglobin, Tag Free Protein
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Reactivity: Human
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Human Neuropeptide Y (29-64 peptide) Protein
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Reactivity: Human
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Human CCL11/Eotaxin, Tag Free Protein
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Human CXCL5, Tag Free Protein
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Human ULBP1/NKG2DL1, C-His Tag Protein
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Human IGF-I R/IGF1R, C-His Tag Protein
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Human Apolipoprotein E, Tag Free
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Human IFN-gamma, Tag Free Protein
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Human EPCR/PROCR/CD201, C-His, Flag Tag (ECD) Protein
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Reactivity: Human
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Human ICAM-3/CD50, C-His Tag (ECD) Protein
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Reactivity: Human
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Human MCP-2/CCL8, Tag Free Protein
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Reactivity: Human
Conjugate:
Human CD40/TNFRSF5, C-His Tag Protein
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Reactivity: Human
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Human IL-18, Tag Free (HEK293) Protein
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Reactivity: Human
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Human NAMPT, C-His Tag Protein
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Reactivity: Human
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Human BAFF/BLyS/TNFSF13B, Tag Free (ECD) Protein
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Reactivity: Human
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Human ACE2, C-His Tag (ECD) Protein
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Reactivity: Human
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Human OX40/TNFRSF4, C-His Tag Protein
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Reactivity: Human
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Reactivity: Human
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Human Fas Ligand/TNFSF6, Tag Free Protein
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
Conjugate:
Human IL-33, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human VEGF-D, Tag Free Protein
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Reactivity: Human
Conjugate:
Human CCL24/Eotaxin-2/MPIF-2, Tag Free Protein
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Reactivity: Human
Conjugate:
Human Tissue Factor, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human CD21/CR2, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-17A, Tag Free Protein
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Reactivity: Human
Conjugate:
Human beta-NGF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD155/PVR, C-His Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human ACE, Tag Free Protein
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Reactivity: Human
Conjugate:
Human IFN-alpha/beta R2, C-His Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human IL-3, Tag Free Protein
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Reactivity: Human
Conjugate:
Human TNF-alpha, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Lipocalin-2/NGAL, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human IL12RB1, C-His Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human ICOS Ligand/B7-H2/ICOSLG, C-His Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human DR6 / TNFRSF21, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human CXCL2/GRO beta, Tag Free Protein
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Reactivity: Human
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Human CXCL4/PF4, Tag Free Protein
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Reactivity: Human
Conjugate:
Human Siglec-3/CD33, Tag Free Protein
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Reactivity: Human
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Human Apolipoprotein M/APOM, Tag Free
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Reactivity: Human
Conjugate:
Human GHRL, C-His, Flag Tag Protein
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Reactivity: Human
Conjugate:
Human Serum Amyloid P-component/APCS, Tag Free Protein
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Reactivity: Human
Conjugate:
Human FGFR2, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human CEACAM-5/CD66e, Tag Free Protein
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Reactivity: Human
Conjugate:
Human BAFF/TNFSF13B/CD257 Trimer design, Tag Free Protein
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Reactivity: Human
Conjugate:
Human HBEGF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Syndecan-1/CD138, C-His Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human FGF Basic/FGF2, Tag Free Protein
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Reactivity: Human
Conjugate:
Human ICAM-2/CD102, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human IL5RA, C-His Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human CDCP1, Tag Free Protein
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Reactivity: Human
Conjugate:
Human CSF3R/G-CSFR/CD114, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human IL17RA/CD217, C-His Tag (ECD) Protein
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
Human IL-13 R alpha 2/IL13RA2, Tag Free (ECD) Protein
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Reactivity: Human
Conjugate:
Human E-Selectin/CD62E, Tag Free (ECD) Protein
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Reactivity: Human
Conjugate:
Human Endoglin/CD105, C-His Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human CD47, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Fas/TNFRSF6/CD95, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-21, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-25/IL-17E, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL6/GCP-2, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human N-Cadherin, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-17F, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL27, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD155/PVR, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Pro-neuropeptide Y, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD163, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Fetuin A/AHSG, Tag Freee Protein
Application:
Reactivity: Human
Conjugate:
Human M-CSFR/CSF1R/CD115, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human TNFSF11/RANKL/CD254, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Ficolin-2, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human L-selectin/CD62L, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human HCLS1, N-Strep II, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-10RB, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Angiogenin, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL1RA, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-1 RII, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD30/TNFRSF8, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human VEGF165, Tag Free Protein
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Reactivity: Human
Conjugate:
Human CALCA, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Nectin-2, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human HGF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD83, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Fractalkine/CX3CL1, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
Human CCL25/TECK, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-8/CXCL8 Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human LAG-3, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD40 Ligand/TNFSF5, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CKMB heterodimer, C-Flag, StrepII Tag&C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD147/Basigin/EMMPRIN, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Apolipoprotein E/APOE4 (C130R), Tag Free
Application:
Reactivity: Human
Conjugate:
Human IL-10, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human HGF, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human B7-1/CD80, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL5/RANTES, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL26/Eotaxin-3, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human tPA, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Angiotensinogen, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CCL20, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Renin, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human TNF-alpha, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-3R alpha/CD123, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-7, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CDC42, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Transthyretin/TTR, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Haptoglobin/HP, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human uPAR/PLAUR, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Apolipoprotein A-I/APOA1, Tag Free
Application:
Reactivity: Human
Conjugate:
Human IL-13, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD28, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human MAPK12, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IFN-alpha/beta R1, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD58/LFA-3, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-21, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human RAC1, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-31, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human BST2/Tetherin, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD46, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD117/c-Kit, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human TACI/TNFRSF13B, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-20, C-hFc Tag Protein
Application:
Reactivity: Human
Conjugate:
Human NKp46/NCR1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human GITR Ligand/TNFSF18, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human APOC3, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human NKG2D, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL22 / MDC, C-hFc Tag Protein
Application:
Reactivity: Human
Conjugate:
Human LAP3, C-His Tag (Isoform 2) Protein
Application:
Reactivity: Human
Conjugate:
Human PLGF/PGF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Ferritin heavy chain 1/FTH1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD70/CD27 Ligand/TNFSF7, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Plasminogen/PLG, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human FABP2, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human FGL1, C-hFc Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-2R alpha, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-2RB/CD122, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IFN-gamma, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human 4-1BB/TNFRSF9, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Siglec-7/CD328, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human RBP4, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human G-CSF, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IMMT/Mitofilin, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CASQ2, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-1 beta/IL1B, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human FGF2/b-FGF, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human EGF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-10, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-4, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CKM, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-2, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human HVEM/TNFRSF14, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human ICAM-1/CD54, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human PDGF-B, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human PD-L1/B7-H1, C-hFc Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-16, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human VEGF121, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human TNF RII/TNFRSF1B, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human PD-L1/B7-H1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human B7-H3, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-29/IFN-lambda 1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Osteoprotegerin / TNFRSF11B, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD272/BTLA, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human HVEM/TNFRSF14, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human MAPK6, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD5, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IP-10/CXCL10, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL12/SDF-1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD27/TNFRSF7, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human LILRB1/CD85j/ILT2, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human GITR/TNFRSF18/AITR, C-Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Leptin, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD2, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-1 alpha/IL1A, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Periostin/OSF-2, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-4R, C-His, Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL9, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL2/MCP1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CTLA-4, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD31/PECAM-1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human P-Selectin/CD62P, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Adiponectin/Acrp30, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Beta-2-microglobulin/B2M, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL12B/P40, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human PD-1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human VCAM-1 / CD106, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human VE-cadherin, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human LILRB4/ILT3, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-18 BPa, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD63, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD207, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human ANPEP/CD13, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human B7-DC/PD-L2/CD273, C-Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6R, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human GADD45A, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human TIE2/TEK, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Pentraxin 3/PTX3, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human A2M/alpha-2-macroglobulin, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human NCAM1/CD56, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human DPP-4/CD26/DPPIV, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD14, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CYLD, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL2RG/CD132, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human E-Cadherin, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human TIMP1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Resistin, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human VEGFR2/KDR, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IFN-gamma R1, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Interferon alpha-2/IFNA2, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
