Human PLGF/PGF, Tag Free Protein
Catalog# HA211337
Human PLGF/PGF, Tag Free Protein
Product Information
Product name
Human PLGF/PGF, Tag Free Protein
Catalog No.
HA211337
Predicted molecular mass
15.5 kD
Protein construction description
A DNA sequence encoding the human PLGF/PGF protein (P49763-2) (Leu 19-Arg 149) was expressed with tag free.
Accession
P49763-2
Protein construction
PLGF/PGF (19-149)
Source
HEK293
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
Placental growth factor (PlGF) is a protein that in humans is encoded by the PGF gene. Placental growth factor is a member of the VEGF (vascular endothelial growth factor) sub-family - a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PlGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast. The placental growth factor gene (PGF) is a protein-coding gene and a member of the vascular endothelial growth factor (VEGF) family. PGF is expressed only in human umbilical vein endothelial cells, and the placenta. PGF is ultimately associated with angiogenesis. Specifically, PGF plays a role in trophoblast growth and differentiation. Trophoblast cells, specifically extravillous trophoblast cells, are responsible for invading the uterine wall and the maternal spiral arteries. The extravillous trophoblast cells produce a blood vessel of larger diameter for the developing fetus that is independent of maternal vasoconstriction. This is essential for increased blood flow and reduced resistance. Proper development of blood vessels in the placenta is crucial for the higher blood requirement of the fetus later in pregnancy. Under normal physiologic conditions, PGF is also expressed at a low level in other organs including the heart, lung, thyroid, and skeletal muscle.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Human IL-6, C-His Tag Protein
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Reactivity: Human
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Human IL-6R, C-His (ECD) Protein
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Reactivity: Human
Conjugate:
Human TIE2/TEK, C-His, Flag Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human Pentraxin 3/PTX3, Tag Free Protein
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Reactivity: Human
Conjugate:
Human A2M/alpha-2-macroglobulin, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human MMP-9, C-His, Flag Tag Protein
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Reactivity: Human
Conjugate:
Human Fibronectin/FN1, Tag Free Protein
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Reactivity: Human
Conjugate:
Human GH1, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human PDGF-AA, Tag Free Protein
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
Human Resistin, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
Human Interferon alpha-2/IFNA2, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Prolactin/PRL, C-His, Flag Tag Protein
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
