Human IGF-II/IGF2, Tag Free Protein
Catalog# HA211319
Human IGF-II/IGF2, Tag Free Protein
Product Information
Product name
Human IGF-II/IGF2, Tag Free Protein
Catalog No.
HA211319
Predicted molecular mass
8.3 kD
Protein construction description
A DNA sequence encoding the human IGF-II/IGF2 protein (P01344-1) (Ala 25-Glu 91) was expressed with tag free.
Accession
P01344-1
Protein construction
Source
HEK293
Bio Activity
Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. The ED50 for this effect is 1.8-7 ng/mL.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
IGF-II (Insulin-like growth factor II; also multiplication-stimulating polypeptide/MSP and somatomedin-A) is a secreted 8 kDa polypeptide that belongs to the insulin family of peptide growth factors. It is part of a complex system of growth and metabolic-regulating proteins that is particularly important during development. It has been associated with nervous system proliferation and differentiation, myelination, adrenal cortical proliferation, and skeletal growth and differentiation. In human, IGF-II is primarily synthesized by the liver, and circulates at high levels in both fetus and adult. In rodent, however, IGF-II levels drop after the perinatal period, an effect attributed to the lack of a key gene promoter. This may indicate that postnatally, IGF-II has either a limited, or local effect only in rodent.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
Products with the same target and pathway
Human Beta-NGF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human GTPase HRAS, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human TGF-alpha, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Thrombospondin-1/THBS1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human FGF10, C-Flag Protein
Application:
Reactivity: Human
Conjugate:
Human Oncostatin M/OSM, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Amphiregulin/AREG, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human OSMR, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IKK gamma/NEMO, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Insulin, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human SCF/KITLG, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human VEGF-C, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-7, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-7 R alpha / CD127, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Erythropoietin/EPO, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-2, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human EIF4B, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Caspase-9/CASP9, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human EGFR, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human VEGFR1/FLT1 C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human M-CSF/CSF1 (33-255), C His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Neurotrophin 3/NT-3, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human beta-NGF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IFN-alpha/beta R2, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-3, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Osteopontin/OPN, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human FGFR2, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human FGF-23 (R179Q), Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Angiopoietin-1/ANGPT1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human FGF Basic/FGF2, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CSF3R/G-CSFR/CD114, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human FGF-4, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human M-CSFR/CSF1R/CD115, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human LAMC2, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human FGF19, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human VEGF165, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human HGF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human M-CSF/CSF1 (33-190), Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IFNA1/IFNA13, C-Tag Protein
Application:
Reactivity: Human
Conjugate:
Human HGF, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human 14-3-3 zeta, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-3R alpha/CD123, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-7, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human EPHA2, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human FGF1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human VEGFR3/FLT4, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IFN-alpha/beta R1, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human RAC1, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Flt3 Ligand/FLT3LG, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human SCF/KITLG, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD117/c-Kit, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human SCF/KITLG, Tag Free (26-189) Protein
Application:
Reactivity: Human
Conjugate:
Human PLGF/PGF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human COL1A2, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-2R alpha, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-2RB/CD122, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human G-CSF, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human FGF2/b-FGF, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human EGF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-4, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-2, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human PDGF-B, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human FGF-21, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human VEGF121, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human FGF7, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-4R, C-His, Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IGF1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6R, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human TIE2/TEK, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Fibronectin/FN1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human GH1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human PDGF-AA, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human FGF7, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL2RG/CD132, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human VEGFR2/KDR, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Interferon alpha-2/IFNA2, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Prolactin/PRL, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
