Human Amphiregulin/AREG, C-His Tag Protein
Catalog# HA211382
Human Amphiregulin/AREG, C-His Tag Protein
Product Information
Product name
Human Amphiregulin/AREG, C-His Tag Protein
Catalog No.
HA211382
Predicted molecular mass
20.6 kD
Protein construction description
A DNA sequence encoding the human Amphiregulin/AREG protein (P15514) (Ser 20-Lys 187) was expressed with a His tag at the C-terminus.
Accession
P15514
Protein construction
Amphiregulin/AREG (20-187)
His
Source
HEK293
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
Amphiregulin, also known as AREG, is a protein synthesized as a transmembrane glycoprotein with 252 aminoacids and it is encoded by the AREG gene. in humans. The protein encoded by this gene is a member of the epidermal growth factor (EGF) family. It is a critical autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is a ligand for epidermal growth factor (EGF) and it is related to transforming growth factor alpha (TGF-alpha). This protein interacts with the Epidermal growth factor receptor (EGFR) to promote the growth of normal epithelial cells.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
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