Human IL1R1, C-His Tag Protein
Catalog# HA211261
Human IL1R1, C-His Tag Protein
Product Information
Product name
Human IL1R1, C-His Tag Protein
Catalog No.
HA211261
Predicted molecular mass
38.5 kD
Protein construction description
A DNA sequence encoding the human IL1R1 protein (P14778) (Leu 18-Lys 336) was expressed with a His tag at the C-terminus.
Accession
P14778
Protein construction
IL1R1 (18-336)
His
Source
HEK293
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
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Human TNF RI/TNFRSF1A, Tag Free (ECD) Protein
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Human Leptin Receptor, C-His Tag (ECD) Protein
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Human IL-7, C-His, Flag Tag Protein
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Reactivity: Human
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Human CCL11/Eotaxin, Tag Free Protein
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Human IL-2, C-His Tag Protein
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Human CXCL5, Tag Free Protein
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Human ULBP1/NKG2DL1, C-His Tag Protein
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Human IFN-gamma, Tag Free Protein
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Human APP, C-His Tag (ECD) Protein
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Human LAIR1, N-Twin Strep, C-His, Flag Tag Protein
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Human EPCR/PROCR/CD201, C-His, Flag Tag (ECD) Protein
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Human ICAM-3/CD50, C-His Tag (ECD) Protein
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Human MCP-2/CCL8, Tag Free Protein
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Reactivity: Human
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Human BAFF/BLyS/TNFSF13B, Tag Free (ECD) Protein
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Reactivity: Human
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Human OX40/TNFRSF4, C-His Tag Protein
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Reactivity: Human
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Human IL-18, Tag Free Protein
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Human TRAF3, C-His Tag Protein
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Human GRO gamma/CXCL3, Tag Free Protein
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Human Neuropilin-1/NRP1, C-His Tag (ECD) Protein
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Human LAMP3/CD208, Tag Free Protein
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Human TREM1, C-Hia, Flag Tag Protein
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Human LILRB2/CD85d/ILT4, C-His, Flag Tag (ECD) Protein
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Human CSK, C-His Tag Protein
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Reactivity: Human
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Human CD2, N-Twin Strep, C-His, Flag Tag Protein
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Human IL-33, C-His Tag Protein
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Human IL-17A, Tag Free Protein
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Reactivity: Human
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Human beta-NGF, Tag Free Protein
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Reactivity: Human
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Human CD155/PVR, C-His Tag (ECD) Protein
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Reactivity: Human
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Human ACE, Tag Free Protein
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Reactivity: Human
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Human IFN-alpha/beta R2, C-His Tag (ECD) Protein
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Reactivity: Human
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Human IL-3, Tag Free Protein
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Reactivity: Human
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Human TNF-alpha, C-His Tag Protein
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Reactivity: Human
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Human IL12RB1, C-His Tag (ECD) Protein
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Human ICOS Ligand/B7-H2/ICOSLG, C-His Tag (ECD) Protein
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Human CXCL2/GRO beta, Tag Free Protein
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Reactivity: Human
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Human Siglec-3/CD33, Tag Free Protein
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Human CEACAM-5/CD66e, Tag Free Protein
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Reactivity: Human
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Human Syndecan-1/CD138, C-His Tag (ECD) Protein
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Reactivity: Human
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Human IL5RA, C-His Tag (ECD) Protein
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Human CSF3R/G-CSFR/CD114, C-His Tag Protein
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Reactivity: Human
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Reactivity: Human
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Human IL1RL1/DER4/ST2, C-hFc, His (ECD) Protein
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Reactivity: Human
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Human IL-13 R alpha 2/IL13RA2, Tag Free (ECD) Protein
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Reactivity: Human
Conjugate:
Human E-Selectin/CD62E, Tag Free (ECD) Protein
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Reactivity: Human
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Human Endoglin/CD105, C-His Tag (ECD) Protein
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Reactivity: Human
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Human CD47, C-His Tag (ECD) Protein
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Reactivity: Human
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Human Fas/TNFRSF6/CD95, C-His Tag (ECD) Protein
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Reactivity: Human
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Human IL-21, Tag Free Protein
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Reactivity: Human
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Human IL-25/IL-17E, Tag Free Protein
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Reactivity: Human
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Human CXCL6/GCP-2, Tag Free Protein
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Reactivity: Human
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Reactivity: Human
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Human IL-17F, Tag Free Protein
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Reactivity: Human
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Human CCL27, Tag Free Protein
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Reactivity: Human
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Human CD155/PVR, Tag Free (ECD) Protein
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Reactivity: Human
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Human CD163, Tag Free (ECD) Protein
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Human TNFSF11/RANKL/CD254, Tag Free Protein
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Human IL-10RB, C-His Tag Protein
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Human LTA, Tag Free Protein
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
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Human Fractalkine/CX3CL1, C-His Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human CXCL11/I-TAC, Tag Free Protein
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Reactivity: Human
Conjugate:
Human MCP-4/CCL13, Tag Free Protein
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Reactivity: Human
Conjugate:
Human CEACAM-1/CD66a, C-His Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human CD200, C-His Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human CCL25/TECK, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-8/CXCL8 Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human LAG-3, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD40 Ligand/TNFSF5, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD147/Basigin/EMMPRIN, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-10, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human B7-1/CD80, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL5/RANTES, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL26/Eotaxin-3, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL20, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human TNF-alpha, Tag Free Protein
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Reactivity: Human
Conjugate:
Human IL-3R alpha/CD123, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human IL-7, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CDC42, Tag Free Protein
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Reactivity: Human
Conjugate:
Human uPAR/PLAUR, Tag Free Protein
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Reactivity: Human
Conjugate:
Human IL-13, Tag Free Protein
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Reactivity: Human
Conjugate:
Human CD28, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human TGF-beta RII, Tag Free (ECD) Protein
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Reactivity: Human
Conjugate:
Human MAPK12, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human IFN-alpha/beta R1, C-His (ECD) Protein
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Reactivity: Human
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Human CD58/LFA-3, C-His Tag (ECD) Protein
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Reactivity: Human
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Human IL-21, C-His, Flag Tag Protein
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Reactivity: Human
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Human RAC1, C-Flag Tag Protein
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Reactivity: Human
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Human IL-31, C-Flag Tag Protein
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Reactivity: Human
Conjugate:
Human BST2/Tetherin, Tag Free Protein
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Reactivity: Human
Conjugate:
Human CD46, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Tau/Tau758, C-His (isoform PNS-tau) Protein
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Reactivity: Human
Conjugate:
Human TACI/TNFRSF13B, Tag Free Protein
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Reactivity: Human
Conjugate:
Human IL-20, C-hFc Tag Protein
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Reactivity: Human
Conjugate:
Human NKp46/NCR1, Tag Free Protein
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Reactivity: Human
Conjugate:
Human GITR Ligand/TNFSF18, Tag Free Protein
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Reactivity: Human
Conjugate:
Human IL-2R alpha, Tag Free Protein
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Reactivity: Human
Conjugate:
Human IL-2RB/CD122, C-His Tag (ECD) Protein
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Reactivity: Human
Conjugate:
Human IFN-gamma, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human 4-1BB/TNFRSF9, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Siglec-7/CD328, C-His (ECD) Protein
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Reactivity: Human
Conjugate:
Human CRKL, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human IL-1 beta/IL1B, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human EGF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-10, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human IL-4, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-2, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human HVEM/TNFRSF14, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human ICAM-1/CD54, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human PD-L1/B7-H1, C-hFc Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-16, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human TNF RII/TNFRSF1B, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human PD-L1/B7-H1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human B7-H3, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-29/IFN-lambda 1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Osteoprotegerin / TNFRSF11B, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD272/BTLA, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human HVEM/TNFRSF14, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human MAPK6, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human MAP4K1/HPK1, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD5, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IP-10/CXCL10, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL12/SDF-1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD27/TNFRSF7, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human LILRB1/CD85j/ILT2, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human GITR/TNFRSF18/AITR, C-Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD2, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-1 alpha/IL1A, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human cIAP-2/BIRC3, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-4R, C-His, Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL9, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL2/MCP1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CTLA-4, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD31/PECAM-1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human P-Selectin/CD62P, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL12B/P40, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human PD-1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Tau/Tau441, C-His (isoform 2N4R) Protein
Application:
Reactivity: Human
Conjugate:
Human VCAM-1 / CD106, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human VE-cadherin, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human LILRB4/ILT3, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-18 BPa, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD63, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD207, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human ANPEP/CD13, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human B7-DC/PD-L2/CD273, C-Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6R, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human GADD45A, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human TIE2/TEK, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human NCAM1/CD56, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human DPP-4/CD26/DPPIV, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD14, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CYLD, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL2RG/CD132, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human E-Cadherin, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human TIMP1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human VEGFR2/KDR, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IFN-gamma R1, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
