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Human 4-1BB/TNFRSF9, C-His Tag Protein (HA210839)

Price: Regular price $389.00

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Catalog# HA210839

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  • Human

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Product Details

Product Type

Protein

Product Name

Human 4-1BB/TNFRSF9, C-His Tag Protein (HA210839)

Predicted molecular mass

18.7 kD

Protein construction description

A DNA sequence encoding the human 4-1BB/TNFRSF9 protein (Q07011) (Leu 24-Gln 186) was expressed with a His tag at the C-terminus.

Accession

Q07011

Protein construction

4-1BB/TNFRSF9 (24-186) | His

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20C to -80C It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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