Human CEBP Beta, Tag Free Protein
Catalog# HA211647
Human CEBP Beta, Tag Free Protein
Product Information
Product name
Human CEBP Beta, Tag Free Protein
Catalog No.
HA211647
Predicted molecular mass
27 kD
Protein construction description
A DNA sequence encoding the human CEBP Beta protein (P17676-1) (Met 1-Ser 261) was expressed with tag free.
Accession
P17676-1
Protein construction
CEBP Beta (1-261)
Source
HEK293
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
The protein encoded by this intronless gene is a bZIP transcription factor that can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. CEBP-beta is critical for normal macrophage functioning, an important immune cell sub-type; mice unable to express CEBP-beta have macrophages that cannot differentiate (specialize) and thus are unable to perform all their biological functions - including macrophage-mediated muscle repair. Observational work has shown that expression of CEBP-beta in blood leukocytes is positively associated with muscle strength in humans, emphasizing the importance of the immune system, and particularly macrophages, in the maintenance of muscle function. Function of CEBPB gene can be effectively examined by siRNA knockdown based on an independent validation.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
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Reactivity: Human
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Reactivity: Human
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
Human Siglec-3/CD33, Tag Free Protein
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Reactivity: Human
Conjugate:
Human LAG-3, Tag Free Protein
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
Human FGF Basic/FGF2, Tag Free Protein
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
Human TAG1/Contactin 2/CNTN2, Tag Free Protein
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Reactivity: Human
Conjugate:
Human Autotaxin/ENPP-2, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CEACAM-6/CD66c, C-His Tag Protein
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Reactivity: Human
Conjugate:
Human Serum Amyloid P-component/APCS, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human c-Fos, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human ICOS Ligand/B7-H2/ICOSLG, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CSK, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human LAMP3/CD208, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CDCP1/CD318, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human PRDM1, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human ULBP1/NKG2DL1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Endoglin/CD105, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Leptin Receptor, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Beta-NGF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human ACE2, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human BAFF/TNFSF13B/CD257 Trimer design, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD47, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Serpin F1/PEDF, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human 5'-nucleotidase/CD73/NT5E, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human FABP3 / H-FABP, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD40 Ligand/TNFSF5, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CKMB heterodimer, C-Flag, StrepII Tag&C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD147/Basigin/EMMPRIN, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Apolipoprotein E/APOE4 (C130R), Tag Free
Application:
Reactivity: Human
Conjugate:
Human IL-10, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human HGF, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human B7-1/CD80, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL5/RANTES, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL26/Eotaxin-3, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human tPA, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Angiotensinogen, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CCL20, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Renin, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human TNF-alpha, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-3R alpha/CD123, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-7, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
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Application:
Reactivity: Human
Conjugate:
Human MAPK12, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IFN-alpha/beta R1, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD58/LFA-3, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-21, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human RAC1, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-31, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human BST2/Tetherin, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD46, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CD117/c-Kit, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-18 R1 / CD218a, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-20, C-hFc Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Apolipoprotein B-100/APOB, Tag Free
Application:
Reactivity: Human
Conjugate:
Human Alpha-fetoprotein, C-His Tag
Application:
Reactivity: Human
Conjugate:
Human CCL22 / MDC, C-hFc Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Plasminogen/PLG, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Alpha 2 Antiplasmin/SerpinF2, C-HIs Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD21/CR2, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-18, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL3/MIP-1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL12RB1, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-1 beta/IL1B, Tag Free (pro form) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-2R alpha, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-2RB/CD122, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IFN-gamma, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human 4-1BB/TNFRSF9, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Siglec-7/CD328, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-17F, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human G-CSF, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IMMT/Mitofilin, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CASQ2, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human FGF2/b-FGF, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human EGF, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-10, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-2, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human ICAM-1/CD54, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human PD-L1/B7-H1, C-hFc Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-16, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human VEGF121, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human TNF RII/TNFRSF1B, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human B7-H3, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human HCLS1, N-Strep II, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD272/BTLA, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human HVEM/TNFRSF14, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human MAPK6, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IP-10/CXCL10, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL12/SDF-1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human IL-1 RII, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD27/TNFRSF7, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human VEGF165, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CALCA, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human LILRB1/CD85j/ILT2, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human GITR/TNFRSF18/AITR, C-Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Leptin, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CEACAM-1/CD66a, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD200, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD2, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-1 alpha/IL1A, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human Periostin/OSF-2, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-4R, C-His, Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL9, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CCL2/MCP1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human CTLA-4, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD31/PECAM-1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human P-Selectin/CD62P, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Adiponectin/Acrp30, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Beta-2-microglobulin/B2M, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL12B/P40, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human PD-1, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human VCAM-1 / CD106, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human VE-cadherin, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human LILRB4/ILT3, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-18 BPa, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CD63, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD207, C-Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human ANPEP/CD13, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CXCL1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human B7-DC/PD-L2/CD273, C-Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL-6R, C-His (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human GADD45A, N-Twin Strep, C-His, Flag Tag Protein
Application:
Reactivity: Human
Conjugate:
Human TIE2/TEK, C-His, Flag Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Pentraxin 3/PTX3, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human A2M/alpha-2-macroglobulin, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human NCAM1/CD56, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human DPP-4/CD26/DPPIV, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human CD14, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human CYLD, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
Human IL2RG/CD132, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human E-Cadherin, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human TIMP1, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human Resistin, Tag Free Protein
Application:
Reactivity: Human
Conjugate:
Human VEGFR2/KDR, Tag Free (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human IFN-gamma R1, C-His Tag (ECD) Protein
Application:
Reactivity: Human
Conjugate:
Human Interferon alpha-2/IFNA2, C-His Tag Protein
Application:
Reactivity: Human
Conjugate:
